A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.

@article{Egerod2012AML,
  title={A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.},
  author={Kristoffer Lihme Egerod and Maja Storm Engelstoft and Kaare Villum Grunddal and Mark K N{\o}hr and Anna Secher and Ichiro Sakata and Jens P. Pedersen and Johanne Agerlin Windel{\o}v and Ernst-Martin F{\"u}chtbauer and J{\o}rgen L. Olsen and Frank Sundler and Jan Pravsgaard Christensen and Nils Wierup and Jesper V. Olsen and Jens Juul Holst and Jeffrey M Zigman and Steen Seier Poulsen and Thue W Schwartz},
  journal={Endocrinology},
  year={2012},
  volume={153 12},
  pages={
          5782-95
        }
}
Enteroendocrine cells such as duodenal cholecystokinin (CCK cells) are generally thought to be confined to certain segments of the gastrointestinal (GI) tract and to store and release peptides derived from only a single peptide precursor. In the current study, however, transgenic mice expressing enhanced green fluorescent protein (eGFP) under the control of the CCK promoter demonstrated a distribution pattern of CCK-eGFP positive cells that extended throughout the intestine. Quantitative PCR… CONTINUE READING

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