A major human thyroglobulin epitope defined with monoclonal antibodies is mainly recognized by human autoantibodies

@article{Henry1992AMH,
  title={A major human thyroglobulin epitope defined with monoclonal antibodies is mainly recognized by human autoantibodies},
  author={Mireille Henry and Eric Zanelli and Martine Piechaczyk and Bernard Christian Pau and Yves Malthi{\'e}ry},
  journal={European Journal of Immunology},
  year={1992},
  volume={22}
}
The antigenic nature of 15 anti‐human thyroglobulin (hTg) monoclonal antibody (mAb) epitopes was studied by two different approaches. First, we tested two successive protease‐digest products of hTg. Only four mAb from the same cluster of reactivity recognized a low‐molecular weight peptide, the other mAb only bound native hTg or high‐molecular weight digest fractions. Second, these 15 mAb were used to immunoscreen hTg expression libraries. Only the same four mAb revealed immunoreactive clones… 
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TLDR
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TLDR
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