A major histocompatibility complex class I allele shared by two species of chimpanzee

@article{Cooper1998AMH,
  title={A major histocompatibility complex class I allele shared by two species of chimpanzee},
  author={Stewart Cooper and Erin J. Adams and Randall S. Wells and Christopher M Walker and Peter Parham},
  journal={Immunogenetics},
  year={1998},
  volume={47},
  pages={212-217}
}
 Little is known regarding the rates at which natural selection can modify or retain antigen presenting alleles at the major histocompatibility complex (MHC). Discovery of identical [1101 base pairs (bp)] coding regions at the MHC class I C locus in Pan troglodytes and Pan paniscus, chimpanzee species that diverged ∼2.3 million years ago, now indicates that a class I allotype can survive for at least this period. Remarkable conservation was also reflected in the (1799 bp) introns where a… CONTINUE READING
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Current Protocols in Molecular Biology

  • F. M. Ausubel
  • 1987
Highly Influential
2 Excerpts

The evolution of major histocompatibility complex class I genes in primates

  • D. I. Watkins
  • Crit Rev Immunol
  • 1995
2 Excerpts