A macroporous hydrogel for the coculture of neural progenitor and endothelial cells to form functional vascular networks in vivo.

@article{Ford2006AMH,
  title={A macroporous hydrogel for the coculture of neural progenitor and endothelial cells to form functional vascular networks in vivo.},
  author={Millicent C Ford and James P. Bertram and Sara Royce Hynes and Michael James Michaud and Qingquan Li and Michael Benjamin Young and Steven S Segal and Joseph A. Madri and Erin B Lavik},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 8},
  pages={
          2512-7
        }
}
A microvascular network is critical for the survival and function of most tissues. We have investigated the potential of neural progenitor cells to augment the formation and stabilization of microvascular networks in a previously uncharacterized three-dimensional macroporous hydrogel and the ability of this engineered system to develop a functional microcirculation in vivo. The hydrogel is synthesized by cross-linking polyethylene glycol with polylysine around a salt-leached polylactic-co… CONTINUE READING

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Bioconjugate Techniques (Academic, San Diego)

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