A macrophage migration inhibitory factor like oxidoreductase from pearl oyster Pinctada fucata involved in innate immune responses.

@article{Cui2011AMM,
  title={A macrophage migration inhibitory factor like oxidoreductase from pearl oyster Pinctada fucata involved in innate immune responses.},
  author={Shuge Cui and Dian-chang Zhang and Shigui Jiang and Hanlin Pu and Yuting Hu and Huayang Guo and Mingqiang Chen and Tanfeng Su and Caiyan Zhu},
  journal={Fish & shellfish immunology},
  year={2011},
  volume={31 2},
  pages={173-81}
}
Macrophage migration inhibitory factor (MIF) is an important cytokine and plays a crucial role as a pivotal regulator of innate immunity. In this study, a MIF cDNA was identified and characterized from the pearl oyster Pinctada fucata (designated as PoMIF). The full-length of PoMIF was 1544 bp and consisted of a 5'-untranslated region (UTR) of 45 bp, a 3'-UTR of 1139 bp with a polyadenylation signal (AATAAA) at 12 nucleotides upstream of the poly (A) tail. The open reading frame (ORF) of PoMIF… CONTINUE READING
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