A macro creatine kinase isoenzyme in serum of apparently healthy individuals.

  title={A macro creatine kinase isoenzyme in serum of apparently healthy individuals.},
  author={Peter Whelan and Herbert Malkus},
  journal={Clinical chemistry},
  volume={29 7},
Activity of creatine kinase B subunit, as measured by an immunoinhibition assay, is persistently increased in certain healthy, asymptomatic adults, whose values for total CK activity are within normal limits. Serum samples from two such individuals were investigated by electrophoresis, heat inactivation, determination of activation energies, and immunosorption (on protein A). The results demonstrated the presence of a circulating complex of IgG and CK-BB, which has been described as macro CK… CONTINUE READING

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