A lung model describing uptake of organic solvents and roles of mucosal blood flow and metabolism in the bronchioles.

@article{Kumagai2000ALM,
  title={A lung model describing uptake of organic solvents and roles of mucosal blood flow and metabolism in the bronchioles.},
  author={Shinji Kumagai and Ichiro Matsunaga},
  journal={Inhalation toxicology},
  year={2000},
  volume={12 6},
  pages={491-510}
}
A simple lung model (mucosal blood flow and metabolism model, MBM model) was developed to describe the uptake of organic solvents and investigate the role of mucosal blood flow and metabolism. The model separates the lung into four compartments, the peripheral bronchial tract (gas phase), the mucus layer lining the wall surface of the tract, the alveolar space (gas phase), and the alveolar blood. Solvent molecules are absorbed in the mucus layer during inhalation and released during exhalation… CONTINUE READING

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