A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427

Abstract

Human African Trypanosomiasis (HAT) is caused by two trypanosome species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Current drugs available for the treatment of HAT have significant issues related to toxicity, administration regimes with limited effectiveness across species and disease stages, thus there is a considerable need to find… (More)
DOI: 10.1186/1756-3305-2-54

Cite this paper

@inproceedings{Sykes2009ALB, title={A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427}, author={Melissa L. Sykes and Vicky M. Avery}, booktitle={Parasites & Vectors}, year={2009} }