A lower prevalence of atopy symptoms in children with type 1 diabetes mellitus.

  title={A lower prevalence of atopy symptoms in children with type 1 diabetes mellitus.},
  author={Robbert Meerwaldt and Roelof J H Odink and Ruben Landaeta and Frits Aarts and Bert A Brunekreef and Jorrit Gerritsen and Willem M.C. van Aalderen and Maarten Otto Hoekstra},
  journal={Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology},
  volume={32 2},
BACKGROUND The Th1/Th 2 concept is a model to understand the pathophysiology of certain diseases. Atopic diseases (asthma, eczema and hayfever) are characterized by a chronic inflammatory reaction that is dominated by Th 2 cells, and type 1 diabetes mellitus (DM) is Th1 cell dominated. Because it is known that Th1 and Th 2 cells reciprocally counteract each other, it can be speculated that the prevalence of Th 2-mediated disease is lower in patients with Th1-mediated disease. OBJECTIVE To… CONTINUE READING

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