A low-dose β1-blocker effectively and safely slows the heart rate in patients with acute decompensated heart failure and rapid atrial fibrillation.

@article{Kobayashi2014AL,
  title={A low-dose β1-blocker effectively and safely slows the heart rate in patients with acute decompensated heart failure and rapid atrial fibrillation.},
  author={Shigeki Kobayashi and Wakako Murakami and Takeki Myoren and Hiroki Tateishi and Shinichi Okuda and Masahiro Doi and Tomoko Nao and Yasuaki Wada and Masunori Matsuzaki and Masafumi Yano},
  journal={Cardiology},
  year={2014},
  volume={127 2},
  pages={105-13}
}
OBJECTIVE Recently, we reported that low-dose landiolol (1.5 µg·kg(-1)·min(-1)), an ultra-short-acting β-blocker, safely decreased the heart rate (HR) in patients with acute decompensated heart failure (ADHF) and sinus tachycardia, thereby improving cardiac function. We investigated whether low-dose landiolol effectively decreased the HR in ADHF patients with rapid atrial fibrillation (AF). METHODS We enrolled 23 ADHF patients with rapid AF (HR ≥120 beats·min(-1) and New York Heart… CONTINUE READING
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