A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere.

@article{Takahashi1992ALC,
  title={A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere.},
  author={Kazuaki Takahashi and Shin Murakami and Yuji Chikashige and Hironori Funabiki and Osami Niwa and Mitsuhiro Yanagida},
  journal={Molecular biology of the cell},
  year={1992},
  volume={3 7},
  pages={
          819-35
        }
}
Fission yeast centromeres vary in size but are organized in a similar fashion. Each consists of two distinct domains, namely, the approximately 15-kilobase (kb) central region (cnt+imr), containing chromosome-specific low copy number sequences, and 20- to 100-kb outer surrounding sequences (otr) with highly repetitive motifs common to all centromeres. The central region consists of an inner asymmetric sequence flanked by inverted repeats that exhibit strict identity with each other. Nucleotide… CONTINUE READING
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