A longitudinal proton magnetic resonance spectroscopy study investigating oxidative stress as a result of alcohol and tobacco use in youth with bipolar disorder.

@article{Chitty2015ALP,
  title={A longitudinal proton magnetic resonance spectroscopy study investigating oxidative stress as a result of alcohol and tobacco use in youth with bipolar disorder.},
  author={Kate M Chitty and Jim Lagopoulos and Ian B. Hickie and Daniel F Hermens},
  journal={Journal of affective disorders},
  year={2015},
  volume={175},
  pages={
          481-7
        }
}
  • Kate M Chitty, Jim Lagopoulos, +1 author Daniel F Hermens
  • Published 2015
  • Medicine, Psychology
  • Journal of affective disorders
  • Alcohol and tobacco have been suggested to be "aggravating factors" for neuroprogression in bipolar disorder (BD), however the impact of these substances on the underlying neurobiology is limited. Oxidative stress is a key target for research into neuroprogression in BD and in accordance with this model, our previous cross-sectional studies have found that risky alcohol and tobacco use in BD is associated with increased oxidative stress, investigated via in vivo glutathione (GSH) measured by… CONTINUE READING

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