A longitudinal analysis of wheezing in young children: the independent effects of early life exposure to house dust endotoxin, allergens, and pets.

@article{Litonjua2002ALA,
  title={A longitudinal analysis of wheezing in young children: the independent effects of early life exposure to house dust endotoxin, allergens, and pets.},
  author={Augusto A Litonjua and Donald K. Milton and Juan C Celed{\'o}n and Louise Ryan and Scott T. Weiss and Diane R. Gold},
  journal={The Journal of allergy and clinical immunology},
  year={2002},
  volume={110 5},
  pages={736-42}
}
BACKGROUND It has been postulated that exposure to bacterial endotoxins and animals early in life might confer protection against the development of asthma and allergies. OBJECTIVE We investigated the longitudinal effects of exposure to house dust endotoxin (HDE), allergen levels, and the presence of a dog in the home on wheezing in young children over a 4-year period. METHODS Two hundred twenty-six children younger than 5 years were followed for 4 years. Endotoxin and allergen levels were… CONTINUE READING