A long-term epigenetic memory switch controls bacterial virulence bimodality

@article{Ronin2017ALE,
  title={A long-term epigenetic memory switch controls bacterial virulence bimodality},
  author={Irine Ronin and Naama Katsowich and Ilan Rosenshine and Nathalie Q. Balaban},
  journal={eLife},
  year={2017},
  volume={6}
}
  • Irine Ronin, Naama Katsowich, +1 author Nathalie Q. Balaban
  • Published 2017
  • Biology, Medicine
  • eLife
  • When pathogens enter the host, sensing of environmental cues activates the expression of virulence genes. Opposite transition of pathogens from activating to non-activating conditions is poorly understood. Interestingly, variability in the expression of virulence genes upon infection enhances colonization. In order to systematically detect the role of phenotypic variability in enteropathogenic E. coli (EPEC), an important human pathogen, both in virulence activating and non-activating… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 22 CITATIONS, ESTIMATED 59% COVERAGE

    Environment Controls LEE Regulation in Enteropathogenic Escherichia coli

    VIEW 17 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    2017
    2020

    CITATION STATISTICS

    • 1 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 87 REFERENCES

    Regulation of phenotypic variability by a threshold-based mechanism underlies bacterial persistence

    VIEW 2 EXCERPTS