A long-standing hyperglycaemic condition impairs skin barrier by accelerating skin ageing process.

@article{Park2011ALH,
  title={A long-standing hyperglycaemic condition impairs skin barrier by accelerating skin ageing process.},
  author={Hwa-young Park and Jae-Hong Kim and Minyoung Jung and Choon Hee Chung and Rosnani Hasham and Chang Seo Park and Eung Ho Choi},
  journal={Experimental dermatology},
  year={2011},
  volume={20 12},
  pages={
          969-74
        }
}
Uncontrolled chronic hyperglycaemia including type 2 diabetes mellitus (DM) induces many skin problems related to chronic impaired skin barrier state. However, little is known about the skin barrier state of chronic hyperglycaemia patients, the dysfunction of which may be a major cause of their skin problems. In this study, we investigated whether a long-standing hyperglycaemic condition including type 2 DM impairs skin barrier homoeostasis in proportion to the duration and its pathomechanism… CONTINUE READING

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