A long non-coding RNA contributes to doxorubicin resistance of osteosarcoma

@article{Zhang2015ALN,
  title={A long non-coding RNA contributes to doxorubicin resistance of osteosarcoma},
  author={Chunlin Zhang and K P Zhu and Guo-Qi Shen and Zhong-sheng Zhu},
  journal={Tumor Biology},
  year={2015},
  volume={37},
  pages={2737-2748}
}
Long non-coding RNAs (lncRNAs) are emerging in molecular biology as crucial regulators of cancer. Although the aberrant expression of lncRNAs has been observed in osteosarcoma (OS), the molecular mechanisms underlying lncRNAs in doxorubicin resistance of OS still unknown. In the current study, we investigated a novel lncRNA, termed ODRUL (osteosarcoma doxorubicin-resistance related up-regulated lncRNA), and evaluated its role in the occurrence of doxorubicin resistance in OS. LncRNA microarray… CONTINUE READING
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