A logical analysis of T cell activation and anergy.

  title={A logical analysis of T cell activation and anergy.},
  author={Marcelle Kaufman and Fabienne Andris and Oberdan Leo},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={96 7},
Interaction of the antigen-specific receptor of T lymphocytes with its antigenic ligand can lead either to cell activation or to a state of profound unresponsiveness (anergy). Although subtle changes in the nature of the ligand or of the antigen-presenting cell have been shown to affect the outcome of T cell receptor ligation, the mechanism by which the same receptor can induce alternative cellular responses is not completely understood. A model for explaining both positive (cell proliferation… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 23 extracted citations


Publications referenced by this paper.
Showing 1-2 of 2 references

Kaufman et al

R. J. Hayashi, D. Y. Loh, +3 authors 33–38. Immunology
Proc. Natl. Acad. Sci. USA 96 • 1999

Biological Feedback (CRC Press, Boca Raton, FL)

R. Thomas, R. D’Ari

Similar Papers

Loading similar papers…