A living thick nanofibrous implant bifunctionalized with active growth factor and stem cells for bone regeneration

@inproceedings{Eap2015ALT,
  title={A living thick nanofibrous implant bifunctionalized with active growth factor and stem cells for bone regeneration},
  author={Sandy Eap and Laetitia Keller and Jessica Schiavi and Olivier Huck and L{\'e}andro Jacomine and Florence Fioretti and Christian Gauthier and Victor Sebasti{\'a}n and Pascale Schwint{\'e} and Nadia Benkirane-Jessel},
  booktitle={International journal of nanomedicine},
  year={2015}
}
New-generation implants focus on robust, durable, and rapid tissue regeneration to shorten recovery times and decrease risks of postoperative complications for patients. Herein, we describe a new-generation thick nanofibrous implant functionalized with active containers of growth factors and stem cells for regenerative nanomedicine. A thick electrospun poly(ε-caprolactone) nanofibrous implant (from 700 μm to 1 cm thick) was functionalized with chitosan and bone morphogenetic protein BMP-7 as… CONTINUE READING

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