A live and inactivated Chlamydia trachomatis mouse pneumonitis strain induces the maturation of dendritic cells that are phenotypically and immunologically distinct.

@article{ReyLadino2005ALA,
  title={A live and inactivated Chlamydia trachomatis mouse pneumonitis strain induces the maturation of dendritic cells that are phenotypically and immunologically distinct.},
  author={Jose Rey-Ladino and Kasra M Koochesfahani and Michelle L Zaharik and Caixia Shen and Robert C. Brunham},
  journal={Infection and immunity},
  year={2005},
  volume={73 3},
  pages={1568-77}
}
The intracellular bacterial pathogen Chlamydia trachomatis is a major cause of sexually transmitted disease worldwide. While protective immunity does appear to develop following natural chlamydial infection in humans, early vaccine trials using heat-killed C. trachomatis resulted in limited and transient protection with possible enhanced disease during… CONTINUE READING