A lipid mobilizing factor in serum of tumor-bearing mice

  title={A lipid mobilizing factor in serum of tumor-bearing mice},
  author={Shinichi Kitada and Esther F. Hays and James F. Mead},
There is considerable evidence that the growing tumor requires a source of unsaturated fatty acids, but the nature of this source and the mechanism of mobilizing the fatty acids from it are obscure. These experiments make use of AKR mice with implanted adipose tisue labeled with 1-14C linoleic acid. With this experimental animal, it has been found that: (a) in the normal, fed mouse, fat is mobilized slowly and appears largely as respiratory CO2, following oxidation, (b) in the normal, fasted… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 13 extracted citations

Mechanisms of cancer cachexia.

Physiological reviews • 2009
View 1 Excerpt

Isolation of a novel cancer cachectic factor.

The Proceedings of the Nutrition Society • 1997

Cancer cachexia.

British Journal of Cancer • 1991


Publications referenced by this paper.
Showing 1-2 of 2 references

Brenneman, in "Tumor Lipids: Biochemistry and Metabolism," Edited by Randall Wood, American Oil Chemists

A. A. Spector, D.E

Virus Tumorigenesis and lmmunogenesis," Edited by W.S

E. F. Hays
Ceglowski and H. Friedman, Academic Press, Inc., • 1973
View 1 Excerpt

Similar Papers

Loading similar papers…