A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients.

Abstract

The p53 protein acts as a checkpoint in the cell cycle, either preventing or initiating apoptosis. Since cancer is the unchecked proliferation of cells, p53s role is critical. Thus, we have sought a link between the p53 polymorphisms and apoptosis. Wild-type p53 tumor suppressor gene exhibits several common single nucleotide polymorphisms (SNP) both in… (More)

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Cite this paper

@article{Biros2002ALB, title={A link between the p53 germ line polymorphisms and white blood cells apoptosis in lung cancer patients.}, author={Erik Biros and Anton Koh{\'u}t and Ivan Biros and Ivan Kalina and Eva Bogyiov{\'a} and J{\'a}n {\vS}tubňa}, journal={Lung cancer}, year={2002}, volume={35 3}, pages={231-5} }