A link between blood coagulation and prophenol oxidase activation in arthropod host defense.

@article{Nagai2000ALB,
  title={A link between blood coagulation and prophenol oxidase activation in arthropod host defense.},
  author={Taku Nagai and Shun-ichiro Kawabata},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 38},
  pages={29264-7}
}
Phenol oxidase, a copper-containing enzyme, is widely distributed not only in animals but also in plants and fungi, which is responsible for initiating the biosynthesis of melanin. Activation of prophenol oxidase in arthropods is important in host defense. However, the prophenol oxidase-activating system remains poorly understood at the molecular level. Here we show that the coagulation cascade of the horseshoe crab Tachypleus tridentatus is linked to prophenol oxidase activation, with the… CONTINUE READING

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