A link between Notch and progesterone maintains the functionality of the rat corpus luteum.

@article{Accialini2015ALB,
  title={A link between Notch and progesterone maintains the functionality of the rat corpus luteum.},
  author={Paula Accialini and Sergio Flores Hern{\'a}ndez and Diana Bas and Maria Camila Pazos and Griselda Irusta and Dalhia Abramovich and Marta Tesone},
  journal={Reproduction},
  year={2015},
  volume={149 1},
  pages={1-10}
}
In this study, we investigated the interaction between the Notch pathway and progesterone to maintain the functionality of the corpus luteum (CL). When Notch signaling is activated, the γ-secretase complex releases the active intracellular domains (NICD) of their receptors, which exert survival effects. We designed studies to analyze whether the in vitro inhibition of Notch affects progesterone production, steroidogenic regulators, apoptotic parameters, and signaling transduction pathways in… CONTINUE READING
3 Citations
48 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…