A light-up fluorescence assay for tumor cell detection based on bifunctional split aptamers.

@article{Sun2018ALF,
  title={A light-up fluorescence assay for tumor cell detection based on bifunctional split aptamers.},
  author={Yuqiong Sun and Baoyin Yuan and Meitao Deng and Qing Wang and Jin Huang and Qiuping P Guo and Jianbo Liu and Xiaohai Yang and Kemin Wang},
  journal={The Analyst},
  year={2018},
  volume={143 15},
  pages={
          3579-3585
        }
}
Light-up aptamers have attracted growing attention due to their advantages of being label-free and having low fluorescence background. In this work, we developed a light-up fluorescence assay for label-free detection of tumor cells based on a bifunctional split aptamer (BFSA) that contained two DNA strands (BFSA-a and BFSA-b). BFSA-a and BFSA-b were… CONTINUE READING