A light-switchable gene promoter system

@article{ShimizuSato2002ALG,
  title={A light-switchable gene promoter system},
  author={S. Shimizu-Sato and E. Huq and J. Tepperman and P. Quail},
  journal={Nature Biotechnology},
  year={2002},
  volume={20},
  pages={1041-1044}
}
Regulatable transgene systems providing easily controlled, conditional induction or repression of expression are indispensable tools in biomedical and agricultural research and biotechnology. [...] Key Result We show here that yeast cells expressing two chimeric proteins, a phytochrome–GAL4-DNA-binding-domain fusion and a PIF3–GAL4-activation-domain fusion, are induced by red light to express selectable or “scorable” marker genes containing promoters with a GAL4 DNA-binding site, and that this induction is…Expand

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