A light-emitting diode light source for imaging of neural activities with voltage-sensitive dyes

@article{Nishimura2006ALD,
  title={A light-emitting diode light source for imaging of neural activities with voltage-sensitive dyes},
  author={Masataka Nishimura and Hiroshi Shirasawa and Wen-Jie Song},
  journal={Neuroscience Research},
  year={2006},
  volume={54},
  pages={230-234}
}
We tested the possibility of using a high-power monochromatic InGaN light-emitting diode (LED) as an excitation light source for real-time optical imaging using the voltage-sensitive dye RH-795. Driven with a custom-designed, non-feedback-controlled constant-current circuit, the LED generated stable light with rapid on/off. The LED was comparable with commonly used halogen lamps in exciting RH-795. Acoustically evoked responses in the auditory cortex recorded with the two light sources were… CONTINUE READING

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