A light and electron microscopic study


The corneal stromal lesions of a case of lattice dystrophy that fulfilled all the clinical and histopathologic criteria of this disease were examined by light and electron microscopy. The lesions were found to consist of two distinct parts: (1) a nonbirefringent mass of disoriented filaments of approximately one-third the diameter of normal stronml collagen fibrils and (2) a second, birefringent part containing -modified stromal lamellas with highly oriented fibrils of normal diameter but increased density. These observations suggest that the normal collagen fibril separates into filaments of smaller diameter ("fibrillary degeneration").

8 Figures and Tables

Citations per Year

5,766 Citations

Semantic Scholar estimates that this publication has 5,766 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@inproceedings{McTigue2005ALA, title={A light and electron microscopic study}, author={John W. McTigue and Ben S. Fine}, year={2005} }