A library of gene expression signatures to illuminate normal and pathological lymphoid biology.

@article{Shaffer2006ALO,
  title={A library of gene expression signatures to illuminate normal and pathological lymphoid biology.},
  author={Arthur L Shaffer and George Wright and Liming Yang and John G. Powell and Vu N. Ngo and Laurence Lamy and Lloyd T Lam and R Eric Davis and Louis M. Staudt},
  journal={Immunological reviews},
  year={2006},
  volume={210},
  pages={67-85}
}
Genomics has provided a lever to pry open lymphoid cells and examine their regulatory biology. The large body of available gene expression data has also allowed us to define the of coordinately expressed genes, termed gene expression signatures, which characterize the states of cellular physiology that reflect cellular differentiation, activation of signaling pathways, and the action of transcription factors. Gene expression signatures that reflect the action of individual transcription factors… CONTINUE READING
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Signatures of the immune response

  • AL Shaffer
  • Immunity
  • 2001
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