A lentiviral vector-based, herpes simplex virus 1 (HSV-1) glycoprotein B vaccine affords cross-protection against HSV-1 and HSV-2 genital infections.

Abstract

Genital herpes is caused by herpes simplex virus 1 (HSV-1) and HSV-2, and its incidence is constantly increasing in the human population. Regardless of the clinical manifestation, HSV-1 and HSV-2 infections are highly transmissible to sexual partners and enhance susceptibility to other sexually transmitted infections. An effective vaccine is not yet… (More)
DOI: 10.1128/JVI.00302-12

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@article{Chiuppesi2012ALV, title={A lentiviral vector-based, herpes simplex virus 1 (HSV-1) glycoprotein B vaccine affords cross-protection against HSV-1 and HSV-2 genital infections.}, author={Flavia Chiuppesi and L. Vannucci and Anna Chiara De Luca and Michele Lai and Barbara Matteoli and Giulia Freer and Roberto Manservigi and Luca Ceccherini-Nelli and F. Maggi and Mauro Bendinelli and Mauro Pistello}, journal={Journal of virology}, year={2012}, volume={86 12}, pages={6563-74} }