A large-scale retrospective study of closing-in behavior in Alzheimer's disease.

@article{Ambron2009ALR,
  title={A large-scale retrospective study of closing-in behavior in Alzheimer's disease.},
  author={Elisabetta Ambron and Robert D. McIntosh and Francesca Allaria and Sergio Della Sala},
  journal={Journal of the International Neuropsychological Society : JINS},
  year={2009},
  volume={15 5},
  pages={
          787-92
        }
}
The frequency and characteristics of closing-in behavior (CIB) were examined in 797 patients with Alzheimer's disease (AD), 132 of whom were followed up longitudinally. The frequency of CIB increased with the complexity of the graphic copying task and with the severity of Alzheimer's disease. Regression analyses suggested that attentional deficits are critical factors for the appearance of CIB, but that visuospatial impairments also play an important role in the emergence of severe forms of CIB… CONTINUE READING

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