A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure.

@article{Corre2009ALA,
  title={A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure.},
  author={Tanguy Corre and Julia Schuettler and Silvia Bione and Anna Marozzi and Luca Persani and Raffaella Rossetti and Francesca Torricelli and Irene Giotti and Peter F. Vogt and Daniela Toniolo},
  journal={Human reproduction},
  year={2009},
  volume={24 8},
  pages={2023-8}
}
BACKGROUND Three variants of the human INHA gene have been reported to be associated with premature ovarian failure (POF) in case-control studies involving a small number of patients and controls. Since inhibin has a fundamental role in the control of ovarian function, it is important to establish the relevance of the reported variants for disease risk. METHODS Three independent POF cohorts, recruited in Northern and Central Italy and in Germany consisting of a total of 611 patients and 1084… CONTINUE READING

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