A large outbreak of typhoid fever associated with a high rate of intestinal perforation in Kasese District, Uganda, 2008-2009.

@article{Neil2012ALO,
  title={A large outbreak of typhoid fever associated with a high rate of intestinal perforation in Kasese District, Uganda, 2008-2009.},
  author={Karen P Neil and Samir V. Sodha and Luswa Lukwago and Shikanga O-Tipo and Matthew L. Mikoleit and Sherricka D Simington and Peter Mukobi and Stephen Balinandi and Samuel Majalija and Joseph Ayers and Atek Atwiine Kagirita and Edward Wefula and Frank Asiimwe and Vianney Kweyamba and Deborah F. Talkington and W. J. Shieh and Patricia Adem and Brigid C. Batten and Sherif R. Zaki and Eric Mintz},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2012},
  volume={54 8},
  pages={1091-9}
}
BACKGROUND Salmonella enterica serovar Typhi (Salmonella Typhi) causes an estimated 22 million typhoid fever cases and 216 000 deaths annually worldwide. In Africa, the lack of laboratory diagnostic capacity limits the ability to recognize endemic typhoid fever and to detect outbreaks. We report a large laboratory-confirmed outbreak of typhoid fever in Uganda with a high proportion of intestinal perforations (IPs). METHODS A suspected case of typhoid fever was defined as fever and abdominal… CONTINUE READING

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