A large family with hereditary MTC: role of RET genetic analysis in differential diagnosis between MEN 2A and FMTC.

@article{Chiefari2001ALF,
  title={A large family with hereditary MTC: role of RET genetic analysis in differential diagnosis between MEN 2A and FMTC.},
  author={Eusebio Chiefari and Rosarita Chiarella and Umberto Crocetti and Berardino Tardio and Franco Arturi and Diego Russo and Vincenzo Trischitta and Sebastiano Filetti and Matteo Zingrillo},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2001},
  volume={33 1},
  pages={52-6}
}
Germline mutations of the RET proto-oncogene cause three different cancer syndromes: multiple endocrine neoplasia type 2A (MEN 2A), multiple endocrine neoplasia type 2B (MEN 2B) and familial medullary thyroid carcinoma (FMTC). In the absence of biochemical and/or clinical evidence of pheochromocytoma and hyperparathyroidism, patients with MEN 2A disease… CONTINUE READING