A label-free aptasensor for the sensitive and specific detection of cocaine using supramolecular aptamer fragments/target complex by electrochemical impedance spectroscopy.

@article{Zhang2012ALA,
  title={A label-free aptasensor for the sensitive and specific detection of cocaine using supramolecular aptamer fragments/target complex by electrochemical impedance spectroscopy.},
  author={De-wen Zhang and Fang-Ting Zhang and Yi-Ran Cui and Qin-pei Deng and Steffi Krause and Ying-Lin Zhou and Xinxiang Zhang},
  journal={Talanta},
  year={2012},
  volume={92},
  pages={65-71}
}
A simple and label-free aptasensor for sensitive and specific detection of cocaine was developed by measuring the change in electrochemical impedance spectra (EIS), based on the formation of a supramolecular aptamer fragments/substrate complex. An anticocaine aptamer was divided into two fragments, Cx and Cy. Three different sensing interfaces, called Au… CONTINUE READING