A lab-on-a-chip platform for studying the subcellular functional proteome of neuronal axons.

Abstract

Axons are long, slender processes extending from the cell bodies of neurons and play diverse and crucial roles in the development and function of nervous systems. Here, we describe the development of a chip device that can be used to produce large quantities of axons for proteomic and RNA analyses. On the chip surface, bundles of axons of rat hippocampal… (More)
DOI: 10.1039/b918217a

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