A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.

@article{Dodding2011AKB,
  title={A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.},
  author={Mark P Dodding and Richard Mitter and Ashley C. Humphries and Michael Way},
  journal={The EMBO journal},
  year={2011},
  volume={30 22},
  pages={4523-38}
}
Transport of cargoes by kinesin-1 is essential for many cellular processes. Nevertheless, the number of proteins known to recruit kinesin-1 via its cargo binding light chain (KLC) is still quite small. We also know relatively little about the molecular features that define kinesin-1 binding. We now show that a bipartite tryptophan-based kinesin-1 binding motif, originally identified in Calsyntenin is present in A36, a vaccinia integral membrane protein. This bipartite motif in A36 is required… CONTINUE READING