A hypothesis on the origin and evolution of tubulin.

  title={A hypothesis on the origin and evolution of tubulin.},
  author={Richard F. Luduena},
  journal={International review of cell and molecular biology},
Tubulin, the protein subunit of microtubules (MTs), is an α/β heterodimer. In this chapter, a hypothesis on the evolution of the tubulin molecule is proposed, based in part on recent reports on the structures and functions of different forms of tubulin and its relatives. The concentration is on three main areas. 1) Evolution of the vertebrate β-tubulin isotypes. In addition to providing a clear idea about the relationships among these isotypes, recent data suggest that tubulin may have… CONTINUE READING

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