A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration.

@article{George2018AHF,
  title={A hypothesis for treating inflammation and oxidative stress with hydrogen sulfide during age-related macular degeneration.},
  author={Akash K. George and Mahavir Singh and Rubens Petit Homme and Avisek Majumder and Harpal S Sandhu and Suresh C Tyagi},
  journal={International journal of ophthalmology},
  year={2018},
  volume={11 5},
  pages={
          881-887
        }
}
Age-related macular degeneration (AMD) is a leading cause of blindness and is becoming a global crisis since affected people will increase to 288 million by 2040. Genetics, age, diabetes, gender, obesity, hypertension, race, hyperopia, iris-color, smoking, sun-light and pyroptosis have varying roles in AMD, but oxidative stress-induced inflammation remains a significant driver of pathobiology. Eye is a unique organ as it contains a remarkable oxygen-gradient that generates reactive oxygen… CONTINUE READING

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