A hydrophobic ligand-binding protein of the Taenia solium metacestode mediates uptake of the host lipid: implication for the maintenance of parasitic cellular homeostasis.

@article{Lee2007AHL,
  title={A hydrophobic ligand-binding protein of the Taenia solium metacestode mediates uptake of the host lipid: implication for the maintenance of parasitic cellular homeostasis.},
  author={Eung-goo Lee and Seon-hee Kim and Young-An Bae and Joon-Yong Chung and Myungkoo Suh and Bessonova Na and Tong-soo Kim and In Sug Kang and Liang Ma and Yoon Kong},
  journal={Proteomics},
  year={2007},
  volume={7 21},
  pages={
          4016-30
        }
}
Parasitic organisms are incapable of de novo fatty acid synthesis due to a down-regulated expression of enzymes involved in the oxygen-dependent pathway. We investigated the uptake of host lipids by a 150-kDa hydrophobic ligand-binding protein (HLBP) of Taenia solium metacestode, an agent causative of neurocysticercosis. The protein was found to be a hetero-oligomeric complex consisting of multiple subunits (M(r) 7, 10, and 15 kDa within pH 8.0-9.7), which may originate from four unique genes… CONTINUE READING
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A recombinant chimeric antigen toward a standardized serodiagnosis of Taenia solium neurocysticercosis.

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  • 2008
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Structural and Binding Properties of Two Paralogous Fatty Acid Binding Proteins of Taenia solium Metacestode

  • PLoS neglected tropical diseases
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