A hydrogel-mineral composite scaffold for osteochondral interface tissue engineering.

@article{Khanarian2012AHC,
  title={A hydrogel-mineral composite scaffold for osteochondral interface tissue engineering.},
  author={Nora T. Khanarian and Jie Jiang and Leo Q. Wan and Van C. Mow and Helen H Lu},
  journal={Tissue engineering. Part A},
  year={2012},
  volume={18 5-6},
  pages={
          533-45
        }
}
Osteoarthritis is the leading cause of physical disability among Americans, and tissue engineered cartilage grafts have emerged as a promising treatment option for this debilitating condition. Currently, the formation of a stable interface between the cartilage graft and subchondral bone remains a significant challenge. This study evaluates the potential of a hybrid scaffold of hydroxyapatite (HA) and alginate hydrogel for the regeneration of the osteochondral interface. Specifically, the… CONTINUE READING

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