A hybrid discrete-continuum mathematical model of pattern prediction in the developing retinal vasculature.

@article{McDougall2012AHD,
  title={A hybrid discrete-continuum mathematical model of pattern prediction in the developing retinal vasculature.},
  author={Steven R. McDougall and Michael G. Watson and Andrea H Devlin and Christopher A. Mitchell and Mark A. J. Chaplain},
  journal={Bulletin of mathematical biology},
  year={2012},
  volume={74 10},
  pages={2272-314}
}
Pathological angiogenesis has been extensively explored by the mathematical modelling community over the past few decades, specifically in the contexts of tumour-induced vascularisation and wound healing. However, there have been relatively few attempts to model angiogenesis associated with normal development, despite the availability of animal models with experimentally accessible and highly ordered vascular topologies: for example, growth and development of the vascular plexus layers in the… CONTINUE READING
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