A human-mouse hybrid cell line that stably expresses chemotaxis to N-formylmethionyl-leucyl-phenylalanine.

@article{Aksamit1986AHH,
  title={A human-mouse hybrid cell line that stably expresses chemotaxis to N-formylmethionyl-leucyl-phenylalanine.},
  author={Robert R. Aksamit},
  journal={Biochemical and biophysical research communications},
  year={1986},
  volume={138 2},
  pages={1001-8}
}
Human leukocytes, which contain monocytes and neutrophils that exhibit chemotaxis to fMet-Leu-Phe, were fused with the mouse macrophage RAW264-TG3 cell line, which exhibits chemotaxis to endotoxin-activated mouse serum but not to fMet-Leu-Phe. From such fusions twelve cell lines were isolated, all of which migrated to endotoxin-activated mouse serum. Four of the cell lines also exhibited chemotaxis to fMet-Leu-Phe, and of these cell lines, only one, WBC264-9, retained the capacity to migrate to… CONTINUE READING