A human immunoglobulinIGHG3 allele (Gmb0, b1, c3, c5, u) with anIGHG4 converted region and three hinge exons

@article{Huck1989AHI,
  title={A human immunoglobulinIGHG3 allele (Gmb0, b1, c3, c5, u) with anIGHG4 converted region and three hinge exons},
  author={Sylvie Huck and G{\'e}rard Lefranc and Marie-Paule Lefranc},
  journal={Immunogenetics},
  year={1989},
  volume={30},
  pages={250-257}
}
The five humanIGHG genes consist of three constant domain exons plus one of or four hinge exon(s), the quadruplicated hinge region being characteristic of theIGHG3 gene. Besides this structural difference, theIGHG genes are polymorphic, as demonstrated by the restriction fragment length polymorphism and, at the protein level, by the Gm allotypic antigenic determinants. In this paper, we report the sequence of theG3m(b0, b1, c3, c5, u) IGHG3 allele, typical of the Black African populations and… CONTINUE READING
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Guidelines for human gene nomenclature (ISGN, HGM9)

  • A M., G. R. Sutherland, M. Traver, N. Van Cong, H. F. Williard
  • Cytogenet Cell Genet
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