A human-human hybridoma which produces antibodies to polioviruses.


A human-human hybridoma which produced antibodies to Sabin strain poliovirus types 3 and 2 was established. This hybridoma was constructed by fusing a HAT-sensitive variant of a human lymphoblastoid subline R4-4-6 with peripheral blood lymphocytes of a donor who had been previously immunized with poliovirus Sabin vaccines and had shown high titer of… (More)


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