A human gut microbial gene catalogue established by metagenomic sequencing

@article{Qin2010AHG,
  title={A human gut microbial gene catalogue established by metagenomic sequencing},
  author={J. Qin and R. Li and J. Raes and Manimozhiyan Arumugam and K. Burgdorf and C. Manichanh and T. Nielsen and N. Pons and F. Levenez and Takuji Yamada and D. Mende and Junhua Li and Junming Xu and Shaochuan Li and Dongfang Li and Jianjun Cao and B. Wang and Huiqing Liang and Huisong Zheng and Y. Xie and J. Tap and P. Lepage and M. Bertalan and Jean-Michel Batto and T. Hansen and D. Paslier and A. Linneberg and H. Nielsen and E. Pelletier and P. Renault and T. Sicheritz-Pont{\'e}n and K. Turner and Hong-mei Zhu and Chang Yu and Shengting Li and Min Jian and Y. Zhou and Yingrui Li and Xiuqing Zhang and Songgang Li and Nan Qin and H. Yang and J. Wang and S. Brunak and J. Dore and F. Guarner and K. Kristiansen and O. Pedersen and J. Parkhill and J. Weissenbach and P. Bork and S. Ehrlich},
  journal={Nature},
  year={2010},
  volume={464},
  pages={59-65}
}
To understand the impact of gut microbes on human health and well-being it is crucial to assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, assembly and characterization of 3.3 million non-redundant microbial genes, derived from 576.7 gigabases of sequence, from faecal samples of 124 European individuals. The gene set, ∼150 times larger than the human gene complement, contains an overwhelming majority of the prevalent (more frequent) microbial genes of… Expand
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