A human folliculoid microsphere assay for exploring epithelial- mesenchymal interactions in the human hair follicle.

@article{Havlickova2009AHF,
  title={A human folliculoid microsphere assay for exploring epithelial- mesenchymal interactions in the human hair follicle.},
  author={Blanka Havlickova and Tam{\'a}s B{\'i}r{\'o} and Alessandra Mescalchin and Miriam Tschirschmann and Hans Joachim Mollenkopf and Albrecht Bettermann and Paolo Pertile and Roland Lauster and Enik{\"o} B{\'o}d{\'o} and Ralf Paus},
  journal={The Journal of investigative dermatology},
  year={2009},
  volume={129 4},
  pages={
          972-83
        }
}
The search for more effective drugs for the management of common hair growth disorders remains a top priority, both for clinical dermatology and industry. In this pilot study, we report a pragmatic organotypic assay for basic and applied hair research. The patented technique produces microdroplets, which generate human folliculoid microspheres (HFMs), consisting of human dermal papilla fibroblasts and outer root sheath keratinocytes within an extracellular matrix that simulates elements of the… CONTINUE READING
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