A human calcium-activated potassium channel gene expressed in vascular smooth muscle.

@article{McCobb1995AHC,
  title={A human calcium-activated potassium channel gene expressed in vascular smooth muscle.},
  author={David P. McCobb and Nina Fowler and Terence Featherstone and Christopher J Lingle and Masao Saito and James E. Krause and Lawrence Salkoff},
  journal={The American journal of physiology},
  year={1995},
  volume={269 3 Pt 2},
  pages={
          H767-77
        }
}
  • David P. McCobb, Nina Fowler, +4 authors Lawrence Salkoff
  • Published in
    The American journal of…
    1995
  • Biology, Medicine
  • Large-conductance Ca(2+)-activated K+ (BK) channels are widespread and functionally heterogeneous. In other classes of K+ channels, functional heterogeneity derives from large gene families, alternative splicing, heterologous subunit composition, and functional modulation. The molecular basis of mammalian BK channel heterogeneity is unknown, since only a single gene (mSlo) has been identified. BK channels in native vascular smooth muscle have an apparent Ca2+ sensitivity approximately 10-fold… CONTINUE READING

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