A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

@article{Yanagi1984AHT,
  title={A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains},
  author={Y. Yanagi and Y. Yoshikai and Kathleen Leggett and S. P. Clark and Ingrid Aleksander and T. Mak},
  journal={Nature},
  year={1984},
  volume={308},
  pages={145-149}
}
We have cloned and sequenced a human mRNA specific for mammalian T-lymphoid cells. The message was found to be expressed in human and murine T lymphoblasts, thymocytes and phytohaemagglutinin-stimulated T lymphocytes. The protein deduced from the cDNA sequence has a molecular weight of 34,938 and shows extensive similarity to the entire length of the variable, joining and constant regions of mammalian immunoglobulin light chains. In addition, the relative positions of the cysteine residues are… Expand
1,168 Citations
A highly homologous T-cell receptor β-chain variable region is expressed in mouse and human T cells
  • 6
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 36 REFERENCES
Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region.
  • G. Matthyssens, T. Rabbitts
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1980
  • 162
  • PDF
Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.
  • J. Parnes, B. Velan, +4 authors J. Seidman
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1981
  • 160
  • PDF
Structure of C-terminal half of two H–2 antigens from cloned mRNA
  • 45
  • PDF
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.
  • N. Hozumi, S. Tonegawa
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1976
  • 598
  • PDF
...
1
2
3
4
...