A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

@article{Yanagi1984AHT,
  title={A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains},
  author={Yusuke Yanagi and Yasunobu Yoshikai and Kathleen Leggett and S. P. Clark and Ingrid Aleksander and Tak Wah Mak},
  journal={Nature},
  year={1984},
  volume={308},
  pages={145-149}
}
We have cloned and sequenced a human mRNA specific for mammalian T-lymphoid cells. The message was found to be expressed in human and murine T lymphoblasts, thymocytes and phytohaemagglutinin-stimulated T lymphocytes. The protein deduced from the cDNA sequence has a molecular weight of 34,938 and shows extensive similarity to the entire length of the variable, joining and constant regions of mammalian immunoglobulin light chains. In addition, the relative positions of the cysteine residues are… 

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