A human Burkitt’s lymphoma cell line carrying t(8;22) and t(14;18) translocations

Abstract

A combination of chromosomal translocations associated with bcl-2 re-arrangement (t(14;18)) and c-myc re-arrangement (t(8;14), t(8;22), or t(2;8)) is a rare event. We describe the first cell line exhibiting t(14;18) and t(8;22), which will enable us to study the interactions of bcl-2 and c-myc systematically. Cell culture was started with circulating… (More)
DOI: 10.1007/s00277-007-0313-7

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