A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription.

@article{Grpin1994AHG,
  title={A hormone-encoding gene identifies a pathway for cardiac but not skeletal muscle gene transcription.},
  author={C. Gr{\'e}pin and L Dagnino and Lynda Robitaille and Linda Haberstroh and T. W. Antakly and M Nemer},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 5},
  pages={
          3115-29
        }
}
In contrast to skeletal muscle, the mechanisms responsible for activation and maintenance of tissue-specific transcription in cardiac muscle remain poorly understood. A family of hormone-encoding genes is expressed in a highly specific manner in cardiac but not skeletal myocytes. This includes the A- and B-type natriuretic peptide (ANP and BNP) genes, which encode peptide hormones with crucial roles in the regulation of blood volume and pressure. Since these genes are markers of cardiac cells… CONTINUE READING

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